【基本情况】

助理研究员，专业方向为分子药理学。

【目前承担课程】

专业必修课——毒理学基础；

通识模块课程——生活中的微生物与健康，Biosafety Training and Environmental Health Safety等。

【主要科研成果】

研究领域主要涉及信号转导通路研究，疾病（主要是抑郁症等神经精神类疾病）的发生机理和生物标记物探索，在国内外期刊发表文章十余篇，代表性论著见下：

1. Weihong Kuang, Mingyue Gao,Liantian Tian, Yang Wan, Peiyuan Qiu. Trends in the prevalence of cognitive impairment in Chinese older adults: based on the Chinese Longitudinal Healthy Longevity Survey cohorts from 1998 to 2014.Int Health. 2020,12: 378-387.

2. Weihong Kuang, Zaiquan Dong,Liantian Tian, Jin Li. MicroRNA-451a, microRNA-34a-5p, and microRNA221-3p as predictors of response to antidepressant treatment.Braz J Med Biol Res. 2018, 51(7): e7212.

3. Jingyuan Xiong,Liantian Tian, Yongjie Qiu, Ding Sun, Hao Zhang, Mei Wu, Jintao Wang. Evaluation on the thyroid disrupting mechanism of malathion in Fischer rat thyroid follicular cell line FRTL-5.Drug Chem Toxicol. 2018, 41(4): 501-508.

4. Weihong Kuang,Liantian Tian, Lili Yue, Jin Li. Effects of Escitalopram with a Chinese traditional compound Jiuweizhenxin-keli on MMN and P50 of patients with Major Depressive Disorder,Neuropsychiatr Dis Treat. 2016, 2016: 1935-41.

5. Jiayi Chen, Yuqin Yao, Xiaolan Su, Ying Shi, Xuejiao Song, Linshen Xie, Jia You,LiantianTian, Luo Yang, Aiping Fang, Jingyuan Xiong. Comparative RNA-Seq transcriptome analysis on silica induced pulmonary inflammation and fibrosis in mice silicosis model.J. Appl. Toxicol. 2018, 38: 773-782.

6. Weihong Kuang, Zaiquan Dong,Liantian Tian, Jin Li. IGF-1 Defends Against Chronic-Stress Induced Depression in Rat Models of Chronic Unpredictable Mild Stress Through the PI3K/Akt/FoxO3a Pathway.Kaohsiung J Med Sci.2018, 34(7): 370-376.

7. Yu Liu, Haojiang Zuo, Yao Wang,Liantian Tian, Xin Xu, Jingyuan Xiong, Xiaofang Pei. Ethanol promotes apoptosis in rat ovarian granulosa cells via the Bcl-2 family dependent intrinsic apoptotic pathway.Cell Mol Biol (Noisy-le-grand). 2018, 64(1): 118-125.

8. YanxiaWu, JingyuanXiong,LiantianTian, XiaofangPei, Yunrong Chai. Microbial Persisters and Health Care.Modern Preventive Medicine, 2014, 41(05): 908-910.

9. Yirong Li,Liantian Tian, Martin Ligr, Daniels Garrett, Peng Yi, Xinyu Wu, Singh Mandeep, Jianjun Wei, Yongzhao Shao, Lepor Herbert, Ruliang Xu, Zhijie Chang, Zhengxin Wang, Peng Lee. Functional Domains of Androgen Receptor Coactivator p44/Mep50/WDR77 and its Interaction with Smad1.PLoSONE. 2013, 8(5):e64663.

10. Martin Ligr, Patwa Ruzeen Rohintan, Daniels Garrett, Pan Lorraine, Xinyu Wu, Yirong Li,Liantian Tian, Zhenxing Wang, Ruliang Xu, Jingjing Wu, Fan Chen, Jinsong Liu, Jianjun Wei, Peng Lee. Expression and Function of Androgen Receptor Coactivator p44/Mep50 in Ovarian Cancer.PLoS ONE. 2011, 6(10): e26250.

11. LiantianTianandKammermeier Paul J.G protein coupling profile of mGluR6 and expression of G alpha proteins in retinal ON bipolar cells.Visual Neuroscience.2006, 23(6): 909-16.

主持和参与省部级以及国家级科研课题数项，代表性课题有：

1. 四川省卫计委重点研究项目，GRK5多态性在糖尿病易感性和糖代谢关键信号通路中的作用，2016-2018，(16ZD023)。

2. 中国自然科学基金，载脂蛋白ApoA-I模拟多肽D-4F对尘肺纤维化的作用及机理研究，2015/01-2017/12，(81402642)。

3. 中国自然科学基金，天然多酚白藜芦醇对尘肺肺纤维化的作用及机制研究，2016/01-2018/12，(81502768)。

4. 四川省科技厅,多酚类天然产物对尘肺纤维化的作用及机制研究(2015JY0212)。

【获奖情况】

1. 2019年度四川大学通识模块课程最受欢迎教师。

2. Kent State University Graduate Student Research Grant, Kent State University, Kent, OH, 2008.

3. Outstanding Poster Award, Research Conference of the School of Biomedical Sciences, Kent State University, Kent, OH, 2008.

4. Frank G. Standaert Award, The American Society for Pharmacology and Experimental Therapeutics, Annual Meeting at Experimental Biology 2008, San Diego, CA, 2008.

5. Postdoctoral Prostate Cancer Training Award, Department of Defense, 2010.

【联系方式】

ltian0875@163.com