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劳动卫生与环境卫生学系

王正陆

发布时间 :2023-02-20      来源 :       浏览量 :


 

基本情况

博士,劳动卫生与环境卫生学系,特聘副研究员。主要从事环境毒理学,环境污染与人群健康风险评估,及污水流行病学方向的研究工作,在Water Research,Journal of Hazardous Materials 等行业内顶级期刊发表SCI论文30余篇, 其中第一和通讯作者12篇,积累影响因子大于100,担任多本国际杂志的审稿人、特刊编辑。作为负责人承担国家自然科学基金青年基金项目,江苏省“双创博士”项目等科研项目4项。

个人主页https://www.researchgate.net/profile/Wang-Zhenglu

【研究方向】

  1. 神经活性物质的复合毒性研究:关注典型违禁药品及抗抑郁药物与环境颗粒物(包括大气细颗粒物和海洋微塑料)的协同污染及复合毒性机制;

  2. 室内空气污染及人群暴露风险评估:主要关注细颗粒物附着多环芳烃二相水合代谢物致老年人群认知障碍的风险评估及作用机制解析。

    【联系方式】

    华西公共卫生学院科教楼6楼, E-mailm18018567955@163.com,Tel.18401649659

【主持科研项目】

  1. 国家自然科学基金青年基金项目, 42007370, 环境浓度下甲基苯丙胺和氯胺酮的联合神经毒性及机制研究, 2021/01-2023/12, 负责人; 在研;

  2. 江苏省“双创博士”项目, B2007215, 基于污水流行病学手段监控社区人群健康状况的方法研发,2021/01-2022/12, 负责人; 在研;

  3. 中央高校基础业务费, B210202134, 江苏省城市湖泊滨岸带甲基苯丙胺和氯胺酮的赋存及生态风险评估, 2021/01-2022/12, 负责人; 已结题;

  4. 中央高校基础业务费, B19020066, 典型违禁品氯胺酮对秀丽隐杆线虫的慢性传代毒性及其机制研究, 2019/01-2020/12, 负责人; 已结题。

    【代表性研究论文】

    2022 年

    Shuiping.Dai, Zhenglu.Wang*,Ying. Yang, Peng. Du, Xiqing Li. PM2.5 induced weight loss of mice through altering theintestinal microenvironment: Mucus barrier, gut microbiota, and metabolic profiling. J. Hazard. Mater. 2022, 431(4):128653.(IF=14.2)

    Jiana Li, Liqi Zhang, Xiaolong Dang, Lei Su, Khalida Jabeen, Hao Wang, Zhenglu Wang*. Effects of cooking methods onmicroplastics in dried shellfish. Sci Total Environ. 2022, 155787 (IF=10.8)

    2021年

    Min.Cai, Zhenglu. Wang*,Haotian. Gu, Hui.Dong, Xu.Zhang, Naxin.Cui, Li.Zhou, Guifa.Chen, Guoyan. Zou*. Occurrenceand temporal variation of antibiotics and antibiotic resistance genes in hospital inpatient department wastewater: Impacts ofdaily schedule of inpatients and wastewater treatment process.Chemosphere. 2021, 292, 133405. (IF= 8.9)

    Shuiping. Dai, Zhenglu. Wang*, Ying. Yang, Xiqing. Li. Ketamine induction of physiological functions alterations inCaenorhabditis elegans by chronic and multigenerational exposure and corresponding aquatic environmental risk assessment.Chemosphere. 2021, 288, 132486. (IF= 8.9)

    Zhenglu. Wang, Shuiping. Dai, Jinze. Wang, Wei. Du*, Lin. Zhu. Assessment on chronic and transgenerationaltoxicity of methamphetamine to Caenorhabditis elegans and associated aquatic risk through toxicity indicator sensitivitydistribution (TISD) analysis. Environ. Pollut. 2021, 288, 117696. (IF= 10.0)

    Zhenglu. Wang, Sheng. Han, Zeqiong. Xu, Peng. Du*, Xiqing. Li. Assessment on the adverse effects on different kinds offish induced by methamphetamine during the natural attenuation process based on adverse outcome pathway. Sci Total Environ.2021, 780, 146587. (IF= 10.8)

    Yungui. Li, Yuqiong. Wang, Jinze. Wang, Long. Chen, Zhenglu. Wang*, Sheng. Feng, Nan. Lin, Wei. Du*. Quantifyindividual variation of realtime PM 2.5 exposure in urban Chinese homes based on a novel method. Indoor Air, 2021, 32(8). (IF= 6.6)

    2020 年

    Zhenglu. Wang, Kang. Mao, Wei. Du, Min. Cai, Zhaobin. Zhang, Xiqing. Li*. Diluted concentrations of methamphetaminein surface water induce behavior disorder, transgenerational toxicity, and ecosystem-level consequences of fish. Water Res. 2020,184, 116164. (IF= 13.4)

    Zhenglu. Wang, Sheng. Han, Min. Cai, Peng. Du, Zhaobin. Zhang, Xiqing. Li*. Environmental behavior ofmethamphetamine and ketamine in aquatic ecosystem: Degradation, bioaccumulation, distribution, and associated shiftin toxicity and bacterial community. Water Res. 2020, 174, 115585. (IF= 13.4)

    Zhenglu. Wang, Zeqiong. Xu, Yuexia. Wu, Zhaobin. Zhang, Xiqing. Li*. Impact of ketamine on the behavior andimmune system of adult medaka (Oryzias latipes) at environmentally relevant concentrations and eco-risk assessment in surfacewater. J. Hazard. Mater. 2020, 393, 121577. (IF=14.2)

    2019 年

    Zhenglu. Wang#, Zeqiong. Xu#, Xiqing. Li*. Impacts of methamphetamine and ketamine on C.elegans’ s physiologicalfunctions at environmentally relevant concentrations and eco-risk assessment in surface waters. J. Hazard. Mater. 2019, 363,268-276.(IF= 14.2)

    2018 年

    Zhenglu. Wang, Zeqiong. Xu, Xiqing. Li*, Biodegradation of methamphetamine and ketamine in aquatic ecosystemand associated shift in bacterial community, J. Hazard. Mater. 2018, 359 356-364.(IF= 14.2)

 


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