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公共卫生与预防医学实验中心

宋雪皎

发布时间 :2022-04-25      来源 :       浏览量 :

说明: F:\博士老电脑资料\IMG_3538.JPG

【基本情况】

博士,四川大学华西公共卫生学院实验师

【目前承担课程】

《分析化学实验》《卫生化学实验》《空气水质理化检验实验》

【主要科研成果】

主持项目:

国家自然科学基金青年项目,81702946,EZH2在直肠癌干细胞中的作用机制及小分子靶向治疗的研究,2018/01-2020/12,20万元,在研,主持

代表性论著:

1.AipingFang#, Shijie Zhou#,XiaolanSu,Liu Chuang, Ciaoxin Chen, YangWan, Xiaohong Lei,LinshenXie, Yiping Jia, Wenzhi Wang,Luo Yang*,XuejiaoSong*, YuqinYao. RAMP3 is a prognostic indicator of liver cancer and might reduce the adverse effect of TP53 mutation on survival,Future Oncol.2018 Jun 8.

2.Xuejiao Song, Tiantao Gao, Qian Lei, Lidan Zhang, Yuqin Yao, Jingyuan Xiong* ,Piperlongumine induces apoptosis in human melanoma cells via mitochondria related intrinsic apoptotic pathway,Nutr Cancer.2018 Apr;70(3):502-511.

3.Xuejiao Song#, Tiantao Gao#, Ningyu Wang, Qiang Feng, Xinyu You, Tinghong Ye, Qian Lei, Yongxia Zhu, Menghua Xiong, Yong Xia, Fangfang Yang, Yaojie Shi, Yuquan Wei, Lidan Zhang, Luoting Yu*, Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer,Sci Rep., 2016, 6: 20864.

4.Xuejiao Song#, Tiantao Gao#, Tinghong Ye, Yongxia Zhu, Qian Lei, Qiang Feng, Bing He, Hongxia Deng, Lidan Zhang, Luoting Yu*, Selective inhibition of EZH2 by ZLD10A blocks H3K27 methylation and kills mutant lymphoma cells proliferation, Biomed Pharmacother, 2016, 81: 288-294.

5.Lidan Zhang#,Xuejiao Song#, Ningyu Wang, Lifeng Zhao, Qiang Feng, Xinyu You, Cuiting Peng, Tiantao Gao,Menghua Xiong, Bing He, Chao Gao, Yong Luo, Ying Xu, Qiyi Zhang, Luoting Yu*, Design, synthesis and biological evaluation of novel 1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolins as potential EZH2 inhibitors, RSC Adv., 2015, 5, 25967-25977.

6.Yong Xia#,Xuejiao Song#, Deliang Li, Tinghong Ye, Hongjun Lin, Nana Meng, Guobo Li, Senyi Deng, Shuang Zhang, Li Liu, Yongxia Zhu, Jun Zeng, Qian Lei, Youli Pan, Yuquan Wei, Yinglan Zhao, Luoting Yu*, YLT192, a novel, orally active bioavailable inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy in preclinical models, Sci Rep., 2014, 4: 6013.

7.Xuejiao Song#, Xia Yong#, Ning-yu Wang, Li-dan Zhang, Xuan-hong Shi, You-zhi Xu, Ting-hong Ye, Yao-jie Shi, Yong-xia Zhu, Luo-ting Yu*, A Novel Benzothiazole Derivative YLT322 Induces Apoptosis via the Mitochondrial Apoptosis Pathway In Vitro with Anti-Tumor Activity in Solid Malignancies,PLoS One,2013, 8(5): e63900.


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